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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS6
All Species:
13.64
Human Site:
S289
Identified Species:
30
UniProt:
Q9UKP5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKP5
NP_922932.2
1117
125273
S289
V
A
K
L
Y
R
D
S
S
L
G
N
V
V
N
Chimpanzee
Pan troglodytes
XP_526907
1117
125238
S289
V
A
K
L
Y
R
D
S
S
L
G
N
V
V
N
Rhesus Macaque
Macaca mulatta
XP_001084793
1117
125301
S289
V
A
K
L
Y
R
D
S
S
L
G
N
V
V
N
Dog
Lupus familis
XP_535255
1117
125043
S289
V
A
K
L
Y
R
D
S
S
L
G
N
V
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
L287
L
G
N
I
V
N
I
L
V
T
R
L
I
L
L
Rat
Rattus norvegicus
Q1EHB3
1595
175796
D358
L
S
C
S
V
S
E
D
T
G
L
P
L
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
L102
H
F
H
L
N
L
T
L
N
T
D
L
V
S
K
Chicken
Gallus gallus
XP_424749
1118
125075
D289
I
V
A
K
L
Y
R
D
S
S
L
G
N
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923204
1116
124633
A288
V
A
K
L
Y
R
D
A
S
L
G
N
V
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
L305
R
S
L
E
D
Y
V
L
T
L
F
S
T
V
A
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
G407
V
A
N
L
Y
H
D
G
S
I
E
N
A
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.4
N.A.
59.7
30.4
N.A.
72.9
92.4
N.A.
82.8
N.A.
N.A.
N.A.
21.4
39.7
Protein Similarity:
100
99.9
99.7
98.9
N.A.
74.4
41.5
N.A.
75.7
95.8
N.A.
90.1
N.A.
N.A.
N.A.
31.1
54.6
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
13.3
13.3
N.A.
93.3
N.A.
N.A.
N.A.
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
26.6
33.3
N.A.
20
20
N.A.
100
N.A.
N.A.
N.A.
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
10
0
0
0
0
10
0
0
0
0
10
10
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
55
19
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
10
0
10
46
10
0
0
0
% G
% His:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
10
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
46
10
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
19
0
10
64
10
10
0
28
0
55
19
19
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
0
10
10
0
0
10
0
0
55
10
0
55
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
46
10
0
0
0
10
0
0
0
0
% R
% Ser:
0
19
0
10
0
10
0
37
64
10
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
10
0
19
19
0
0
10
0
0
% T
% Val:
55
10
0
0
19
0
10
0
10
0
0
0
55
64
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
55
19
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _